Our Focus

Infectious disease is a leading cause of death globally. The rise of multidrug-resistant bacteria and the consequent decline in effective therapies have led to global initiatives to develop new anti-infective drugs and delivery systems. Extherid Bioscience is a specialty contract research organization (CRO) that delivers a range of biological research and development services with a focus on infectious disease. We create innovative solutions by joining basic molecular concepts to clinical applications. Our development of customizable tissue models allows us to explore the molecular mechanisms of multidrug-resistant bacteria that cause infections. We combine molecular experimental approaches to identify drug targets with clinical pharmacology to create new technologies.

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Our Research Areas

Microbial Pathogenesis

Microbial Pathogenesis

We study the pathogenesis of microbes at a skin and mucosal surfaces to identify novel targets for therapy and disease prevention.

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Development of Therapeutics

Development of Therapeutics

We are focused on the development of novel therapeutics to treat and prevent infections caused multi-drug resistant bacteria.

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Research and Development

Research and Development

We deliver a range of biological Research and Development services with a focus on infectious diseases.

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Our Approach

Our long-term goal is to understand host–pathogen interactions at skin and mucosal surfaces, leading to the development of novel therapeutics to treat and prevent infection.

Model

Our Solutions

Tissue Infection Models

Host–pathogen skin and mucosal tissue models to develop novel therapeutics for infection prevention and treatment

  • Tissue Biofilm Models
  • Human Wounded Skin Models
  • Sexually Transmitted Infection Models
  • Tissue Models for Biocompatibility
  • Customizable Tissue Models

Bacterial Virulence Factors

Multidrug-resistant bacterial virulence factors affect host tissues and contribute to disease and biofilm formation

  • Staphylococcus aureus Exotoxin
  • Acinetobacter baumannii Efflux
  • Methicillin-resistant Staphylococcus aureus Cytoxins

Biomarker Identification

Transcriptional and proteomic approaches to identify biomarkers

  • Global Gene Expression
  • Proteomic Determination
  • Pathway Analysis Approaches

Other Research Areas

Expertise, knowledge, and support

  • Cell Culture
  • In Vitro Antimicrobial Susceptibility Analysis
  • Microbial Protein Expression and Characterization
  • Mechanisms of Antibiotic Resistance Determination
  • Preclinical Development of Next Generation Antimicrobials
  • Clinical Pharmacology (Pharmacodynamic and Pharmacokinetic Studies)
  • Bioinformatics (Global Gene Expression and Proteomics)
  • Customized Tissue Model Development

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