Our Focus

Infectious disease remains the second leading cause of death globally. The increase in multi-drug resistant bacteria and the decline in effective therapies are driving global initiatives around developing anti-infective drugs and delivery systems. Extherid Bioscience is a specialty contract research organization (CRO) delivering a range of biological R&D services with a focus on infectious diseases. We create innovative solutions by joining basic molecular concepts to clinical applications. Through the development of customizable tissue models, we explore molecular mechanisms of multi-drug resistant bacteria that lead to infections. We combine these molecular approaches with experimental and clinical pharmacology applications to identify drug targets and create new technologies.

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Our Research Areas

Microbial Pathogenesis

Microbial Pathogenesis

We study the pathogenesis of microbes at a skin and mucosal surfaces to identify novel targets for therapy and disease prevention.

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Development of Therapeutics

Development of Therapeutics

We are focused on the development of novel therapeutics to treat and prevent infections caused multi-drug resistant bacteria.

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Research and Development

Research and Development

We deliver a range of biological Research and Development services with a focus on infectious diseases.

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Our Approach

Our long-term goal is to better understand host-pathogen interactions at skin and mucosal surfaces in order to develop novel therapeutics to treat and prevent infections.

Model

Our Solutions

Tissue Infection Models

Host-pathogen skin and mucosal tissue models to develop novel therapeutics to treat and prevent infections

  • Tissue Biofilm Models
  • Human Wounded Skin Models
  • Sexually Transmitted Infection Models
  • Tissue Models for Biocompatibility
  • Customizable Tissue Models

Bacterial Virulence Factors

Multi-drug resistant bacteria virulence factors effect host tissues and contribute to diseases and biofilm formation

  • Staphylococcus Aureus Exotoxin
  • Acinetobacter Baumannii Efflux
  • Methicillin-resistant Staphylococcus Aureus Cytoxins

Bio Marker Identification

Transcriptional and Proteomic approaches for identification of biomarkers

  • Global Gene Expression
  • Proteomic Determination
  • Pathway Analysis Approaches

Other Research Areas

Expertise, Knowledge and Support

  • Cell Culture
  • In Vitro Antimicrobial Susceptibility Analysis
  • Microbial Protein Expression And Characterization
  • Mechanisms Of Antibiotic Resistance Determination
  • Preclinical Development Of Next Generation Antimicrobials
  • Clinical Pharmacology (Pharmacodynamic and Pharmacokinetic Studies)
  • Bioinformatics (Global Gene Expression And Proteomics)
  • Customized Tissue Model Development

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