Biofilm Reactor

Interested in how your medical device materials inherently disrupt biofilm formation? Our unique biofilm reactor model allows for high throughput testing of the effects of experimental materials on biofilm formation of both gram-positive and gram-negative bacteria.

Model Overview

- We test the antibiofilm properties of biomaterials implanted in the body by means of both static and flow biofilm reactors. Static biofilm reactors reproduce conditions around implants in tissue (e.g., sensors and breast implants), while flow biofilm reactors replicate those found around biomaterials in hollow spaces (e.g., stents and catheters).

Relevant Therapeutic Areas

Medical Devices

Explore how our expertise with tissue models will help your medical devices through clinical trials.

We can use the PMM to test for bacterial adhesion to and host cell toxicity of experimental devices.

Our reactors are an excellent testing platform for materials in development. We can determine how bacteria will adhere, form biofilm, and grow in the presence of your experimental materials.

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Infectious Diseases

Find out how our customizable infectious disease models will help accelerate your preclinical testing to achieve your goals in a cost-effective manner.

Mucosal tissue is an ideal environment for microbial growth, making the PMM an excellent application for testing the efficacy of products to treat infectious disease pathogens. We can test for efficacy against planktonic and biofilm infections with this model.

Porcine skin testing is commonly used to test formulations or compounds that are applied to the skin (e.g., presurgical products). We can track efficacy against host flora or seed the skin with known pathogens and track how they respond to the compound. We can apply this testing to large or small areas of skin.

Our reactors serve as a testing platform for drugs and devices intended to inhibit biofilm formation on abiotic surfaces. We can determine whether or not, and to what degree, bacteria form biofilms in the presence of your materials.

Using our human skin model, we can perform research on known human pathogens. The most common organisms we use are methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aeruginosa, and Acinetobacter baumannii. Infections can be planktonic or biofilm.