Our Models

We perform research on human skin to test for efficacy against known human pathogens. Our most common organisms tested are methicillin-resistant Staphylococcus aureus, and multidrug-resistant Pseudomonas aeruginosa, and Acinetobacter baumannii. Infections tested are planktonic or biofilm.

We perform research on human skin to test for efficacy against known human pathogens. Our most common organisms tested are methicillin-resistant Staphylococcus aureus, and multidrug-resistant Pseudomonas aeruginosa, and Acinetobacter baumannii. Infections tested are planktonic or biofilm.

Our standard model consists of a 5 mm (variable) explant with a smaller wound made inside. The wounds can be burns, incisions, or biopsy punches and can reach varying depths. We assess wound healing progress with biomarker panels and histology.

Our reactors serve as a testing platform for drugs or devices against biofilms grown on abiotic surfaces. We can determine whether bacteria will grow to a biofilm in the presence of your materials.

Our reactors are an excellent testing platform for materials in development. They allow us to determine how bacteria will adhere, form biofilm, and grow in the presence of your developmental materials.

Porcine skin testing is a method for testing formulations or compounds that are applied to skin (e.g., pre-surgical devices). We can test the efficacy of a compound against the host flora or a known seeded pathogen. We apply this testing on large or small areas of skin.

We can use our porcine skin models to study inflammation by testing the tissue for biomarkers known to be involved in inflammatory processes. After treating the skin with experimental formulations, we can analyze for differences in inflammatory cytokine concentrations at various time points.

Porcine skin serves as a relevant model for wound care. The skin has comparable thickness, hair follicle density, and wound closure via reepithelialization.

We apply this model to compounds requiring infectious disease testing. The mucosal tissue serves as an optimal environment for the growing of pathogens. We test against either planktonic or biofilm infections in this model.

This model serves as a unique means of testing for inflammatory cytokines in a cost-effective manner. We can perform ELISAs to determine whether experimental compounds are pro- or anti-inflammatory.

Much of the human genital tract is composed of mucosal tissue. Therefore, this model is excellent for predictive preclinical testing of compounds or products relating to urogenital health.

Using our mucosal model, we can measure bacterial adhesion and host cell toxicity to experimental devices.