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Research

Our Research Areas

Our interdisciplinary team strives to develop novel drug therapies and vaccine strategies for the treatment and prevention of multi-drug resistant bacterial infections and their infectious complications, including non-healing wounds and toxin-mediated diseases. We believe that this process can be streamlined by gaining a better understanding of the basic science of host-pathogen interactions and by using infection models which are predictive of clinical outcomes

Microbial Pathogenesis

Microbial Pathogenesis

We study the pathogenesis of microbes at a skin and mucosal surfaces to identify novel targets for therapy and disease prevention.

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Development of Therapeutics

Development of Therapeutics

We are focused on the development of novel therapeutics to treat and prevent infections caused multi-drug resistant bacteria.

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Research and Development

Research and Development

We deliver a range of biological Research and Development services with a focus on infectious diseases.

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Our Approach

Our long-term goal is to better understand host-pathogen interactions at skin and mucosal surfaces in order to develop novel therapeutics to treat and prevent infections.

Model

Our Solutions

Tissue Infection Models

Host-pathogen skin and mucosal tissue models to develop novel therapeutics to treat and prevent infections

  • Tissue Biofilm Models
  • Human Wounded Skin Models
  • Sexually Transmitted Infection Models
  • Tissue Models for Biocompatibility
  • Customizable Tissue Models

Bacterial Virulence Factors

Multi-drug resistant bacteria virulence factors effect host tissues and contribute to diseases and biofilm formation

  • Staphylococcus Aureus Exotoxin
  • Acinetobacter Baumannii Efflux
  • Methicillin-resistant Staphylococcus Aureus Cytoxins

Bio Marker Identification

Transcriptional and Proteomic approaches for identification of biomarkers

  • Global Gene Expression
  • Proteomic Determination
  • Pathway Analysis Approaches

Other Research Areas

Expertise, Knowledge and Support

  • Cell Culture
  • In Vitro Antimicrobial Susceptibility Analysis
  • Microbial Protein Expression And Characterization
  • Mechanisms Of Antibiotic Resistance Determination
  • Preclinical Development Of Next Generation Antimicrobials
  • Clinical Pharmacology (Pharmacodynamic and Pharmacokinetic Studies)
  • Bioinformatics (Global Gene Expression And Proteomics)
  • Customized Tissue Model Development

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